While sclerotherapy is generally a simple and safe way to remove spider veins, all cosmetic medical procedures carry certain risks associated with that procedure. Some are general medical-related risks and some risks are specific to that procedure.

Risk factors increase for those patients who have certain health issues in their medical history. Other issues that might prohibit patients from undergoing the procedure can be related to blood issues, such as hepatitis, diabetes, heart problems and poor blood circulation.

Procedure specific complications are rare, but may include; allergic reactions (through fluid injections), inflammation, blood clots, increased vein visibility, minor scarring and uneven pigmentation.